Research Associate in Cancer Therapeutics

We have an exciting opportunity in the School of Medicine and Population Health for a Postdoctoral Research Associate position, which is perfect for a researcher with a passion for driving biological discoveries through to development of new cancer therapeutics. It is ideally suited to an enthusiastic researcher looking to use their skills in cancer biology, bone biology, cancer cell dormancy, translational research and/or relevant fields who want to have an impact on patients with incurable cancers that grow in bone (myeloma and advanced breast and prostate cancer).

We are seeking an enthusiastic and motivated researcher to work on the first phase of an 8-year Wellcome Trust-funded award. The project will investigate how dormancy allows cancer cells to evade chemotherapy and identify weaknesses of dormant cell to enable us to develop new dormancy-targeting therapeutics. You will use clinically-relevant in vitro (2D/3D) and in vivo models of multiple myeloma dormancy and chemotherapy-resistance developed by our team. You will test new dormancy and niche-targeting therapeutic approaches to kill dormant cancer cells, and perform multi-omic characterisation of dormant cells and their microenvironment to identify new therapeutic targets.

You should have a PhD or be close to completion in relevant biomedical fields (molecular or cell biology, cancer biology, bone biology) or have equivalent experience. You will be a highly motivated and hard-working with the ability to design, perform and analyse experiments with attention to detail and integrity. The project will include a wide range of models and techniques, experience in cell culture and molecular biology techniques are essential, with experience in large panel flow cytometry and immunofluorescence microscopy being desirable. Experience in mouse models of myeloma/cancer and/or bone would be highly desirable. Experience in metabolomics and/or RNA sequencing and bioinformatics would also be highly desirable..

This is a 3-year post, with potential to extend to 2032. We are committed to exploring flexible working opportunities which benefit the individual and University.

We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development.

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