Research Assistant in MRI of the liver

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Job Description

This is an opportunity for a highly motivated MSc in physics or Engineering to work on a major international EU-fundedb(public-private partnership) research project, Translational Imaging in Drug Safety Assessment (TRISTAN; www.imi-tristan.eu). TRISTAN is a collaboration between partners in academia, industry and SME’s developing new quantitative imaging biomarkers that will help drug developers bring new, safer drugs to market.

Your role will be to support in the development of data analysis and data management strategies to derive imaging biomarkers of hepatocellular function in patients and disease models. The methods will be implemented in international multi-centre clinical studies (UK and Sweden) testing whether these new biomarkers can detect the effect of drugs and predict their interactions. The results will feed into an ongoing process with regulators (FDA) to formally qualify these biomarkers.

The candidate will also work with collaborators to set up a service for academic partners and with SME’s to commercialise these biomarkers.

You will work in the research group of Professor Steven Sourbron, Chair in Medical Imaging Physics and PI of this project in Sheffield, who has a core expertise in quantitative and functional MRI, serving as principal investigator on several international projects including as chair of the COST action on renal MRI (www.renalmri.org), work package lead in the BEAt-DKD project (www.beat-dkd.eu) and past chair of the open source initiative for perfusion imaging (www.osipi.org).

You will benefit from collaborations within TRISTAN, both at the University of Sheffield and internationally with clinicians and basic scientists from broad backgrounds (MRI physics, hepatology, pharmacology). TRISTAN draws heavily on collaborations with the private sector and covers much of Europe, providing an excellent opportunity to scout out different possible career paths.